Yes indeed.
I do it as follows:
First, I use Microangelo to create an .ICL file with a few icons I like.
:: Use 48x48, 32x32 and 16x16 at 256 color only. ::
I Connect the Q to my PC and copy the .ICL to the Windows directory.
Browse to the Start Menu folder of the Windows directory.
Find the shortcut to modify.
Copy it to the PC.
Drop it into Notepad.
You will see:
22#:MSTNOTES
You can specify the icon to use as follows:
22#:MSTNOTES?myicons.icl,-3
myicons.icl is the name of the file I created and -3 means the icon with ID number 3. It's the third icon.
That's it. I've modified damn near every one of my icons using this technique and it's muy sexy..